Infection of Helicobacter pylori
Conditions
Interventions
Sponsors
Jiangnan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Pass the 14C-urea breath test, rapid urease test or histological examination, and be diagnosed with Helicobacter pylori infection within 12 months of enrollment; (2) Aged 18-65 years, male and female; (3) The general health condition is good, but according to the investigator's judgment, whether eradication treatment is needed; (4) Understand the ability required for learning and promise to cooperate with the research during the entire experiment period; (5) Willing to provide written informed consent and basic situation survey form; (6) No anti-pyloric treatment has been performed before.
Exclusion criteria
Exclusion criteria: (1) Gastrointestinal surgery (except appendectomy); (2) Allergy to triple antibiotics or eradication of any contraindications; (3) Pregnant or lactating women; (4) Any historical serious disease (severe cardiovascular, endocrine, liver and kidney dysfunction, etc.) before the eradication of Helicobacter pylori treatment; (5) If the patient took probiotics, antibiotics or research products one month before enrollment, they will also be excluded; (6) Having mental illness, which may cause difficulties in cooperation; (7) Patients who lack self-judgment ability; (8) Alcohol or drug abusers; (9) Subjects participating in other clinical trials; (10) The purpose of the researcher's notification to the researcher; (11) Those that do not meet the research requirements or the researchers think they should not participate in the research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 14C breath test;Fecal Metagenome;Blood biochemical examination;Blood routine examination;anti-Hp IgG;TNF-a;Serum cytokines; | — |
Countries
China
Contacts
Public ContactQixiao Zhai
School of Food Science and Technology, Jiangnan University
Outcome results
None listed