Hypertension
Conditions
Interventions
Treatment plan 1:Valsartan 80mg
Treatment plan 2:Sacubitril Valsartan Sodium 100mg
Treatment plan 3:Sacubitril Valsartan Sodium 200mg
Sponsors
Putuo Hospital, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-80 were diagnosed resistant hypertension; 2. Patients taking 3 or more antihypertensive medications, including one diuretic, who have not yet achieved blood pressure control (> 140/90 mmHg) are referred to as Resistant Hypertension; 3. Signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Secondary hypertension; (2) Patients who had a history of renal artery stenosis or imaging suggestive of renal artery stenosisGFR <45 ml/min /1.73 m2;; (3) Severe liver function damage (Child - Pugh, C); (4) Patients with type 2 diabetes are taking Alighiren; (5) Known existence ACEI or ARB treatment of patients with a history of angioedema always; (6) Genetic or patients with idiopathic angioedema; (7) Pregnant or planning to become pregnant during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| office blood pressure;ambulatory blood pressure; | — |
Countries
China
Contacts
Public ContactLyu Tianjiao
Department of Cardiology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed