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The difference of subgingival microorganism composition among different periodontal conditions and its influence on the prognosis of periodontal initial therapy

Study on the correlation between Entamoeba gingivalis and periodontal condition

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000038928
Enrollment
Unknown
Registered
2020-10-10
Start date
2020-10-15
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periodontal disease

Interventions

periodontal health group:Nil
gingivitis group:Nil
periodontitis group:periodontal initial therapy

Sponsors

Department of Periodontology, West China Stomatological Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: (a)patients with periodontal health 1. Age: 18-45 years old; 2. No obvious inflammation of gingiva; 3. PD = 10%; 4. without CAL; 5. without alveolar bone resorption in radiographic examination. (c)patients with periodontitis 1. Age: 18-45 years old; 2. >= 2 non-adjacent tooth with CAL; 3. PD >= 5mm and CAL >= 4mm; 4. Alveolar bone resorption affects the middle third of the root or beyond.

Exclusion criteria

Exclusion criteria: 1. Body index (BMI) >= 35 or <= 18; 2. Patients with systemic diseases; 3. Patients with abnormal immune function; 4. Patients with organ transplantation; 5. Patients who received periodontal treatment in recent 6 months; 6. Patients who have taken antibiotics in recent 3 months; 7. Patients who have taken other drugs affecting periodontal tissue; 8. Patients with mental diseases; 9. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
probing depth;clinical attachment loss;SBI;PI;tooth mobility;inflammatory factors;detection rate;

Countries

China

Contacts

Public ContactZhao Lei

Department of Periodontology, West China Stomatological Hospital, Sichuan University

jollyzldoc@163.com+86 13551032465

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026