Cardiovascular diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Essential hypertension patients with normal left ventricular ejection fraction (LVEF) >= 50%, 2. According to the 2007 European guidelines for the management of arterial hypertension, patients with hypertension were divided into LVN Group [LVMI 116g / m2 (male) or LVMI > 109G / m2 (female), RWT > 0.42]; 3. Healthy people with the same age and sex were selected as the healthy control group.
Exclusion criteria
Exclusion criteria: 1. Patients with cardiovascular diseases, such as secondary hypertension, coronary heart disease, cardiomyopathy, rheumatic heart disease, congenital heart disease, valvular heart disease, etc.; 2. Patients with diabetes, hyperthyroidism and other endocrine diseases; 3. Patients with cerebrovascular diseases and other systemic diseases; 4. Patients with severe liver and kidney damage, infection and tumor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left ventricular strain;Ambulatory arterial stiffness index;Conventional echocardiography; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood; | — |
Countries
China
Contacts
Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital