Effects of different doses of dizocine on the MACBAR of sevoflurane in patients undergoing laparoscopic pneumoperitoneum stimulus.

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000038916

Enrollment

Unknown

Registered

2020-10-10

Start date

2020-10-01

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients of laparoscopic surgery

Interventions

group one:The diluent of normal saline was pushed statically

group 2:Diluent of normal saline containing 0.1mg/kg dezocine was applied statically

group 3:Diluent of normal saline containing 0.2mg/kg dezocine was applied statically

group 4:Diluent of normal saline containing 0.3mg/kg dezocine was applied statically

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: 100 patients with elective laparoscopic surgery in general surgery, grade ASAI-II, aged 20-65 years, body mass index (BMI)< 30kg/m2.

Exclusion criteria

Exclusion criteria: Intraoperative heart rate (HR) < 50 times/min or mean arterial pressure (MAP)< 50 mmHg; Chronic alcohol and drug abusers; Severely impaired heart, lung, liver and kidney function.

Design outcomes

Primary

Measure	Time frame
heart rate;MACBAR;	—

Countries

China

Contacts

Public ContactYang XiaoLin

Affiliated Hospital of North Sichuan Medical College

yang_xl_yang@126.com+86 13990826183

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026