Patients undergoing laparoscopic cholecystectomy
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age: 18-75 years old; BMI:18-26; 2. Patients diagnosed with gallbladder benign diseases such as gallstone, gallbladder polyp or gallbladder adenomyosis; 3. Patients undergoing elective laparoscopic cholecystectomy; 4. ASA I-II patients; 5. The patients who voluntarily participated in this trial and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who changed the operation mode during the operation; 2. Patients with previous digestive system diseases such as jaundice, cholestasis, liver dysfunction, inflammatory bowel disease, irritable bowel syndrome, intestinal obstruction, rectal prolapse or long-term change of stool habits; patients with previous digestive system or abdominal surgery; patients with previous digestive system or abdominal surgery; 3. Patients who have used gastrointestinal motility drugs, antibiotics, probiotics / prebiotics / synbiotics and other drugs that may change the intestinal flora in the past month; 4. Patients with severe cardiovascular and cerebrovascular diseases and organ failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal flora;Hypersensitive C-reactive protein;bile acid;Interleukin 6;Alpha tumor necrosis factor;Serum amyloid A;Adiponectin;white blood cells;bilirubin;Bristol fecal trait score;interferon ?;?-glutamyl transpeptidase; | — |
Countries
China
Contacts
Wuxi Third People's Hospital