Patients undergoing elective cesarean section
Conditions
Interventions
0IU/h oxytocin group:Oxytocin I.V. infusion
4IU/h oxytocin group:Oxytocin I.V. infusion
12IU/h oxytocin group:Oxytocin I.V. infusion
16IU/h oxytocin group:Oxytocin I.V. infusion
20IU/h oxytocin group:Oxytocin I.V. infusion
Sponsors
Jiaxing Maternity and Child Health Care Hospital (Women and Children Affiliated Hospital, Jiaxing University)
Eligibility
Sex/Gender
Female
Age
35 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. ASA I - II subjects, aged 35-50 years; 2. Singleton pregnancy; 3. The subject of scar uterus; 4. Patients undergoing elective cesarean section; 5. Subjects of abdominal transverse incision; 6. Patients with hemianesthesia; 7. Anesthesia plane T4-T6.
Exclusion criteria
Exclusion criteria: 1. Premature rupture of amniotic membrane in pregnant women entering the stage of labor; 2. Pregnant women with oxytocin allergy; 3. Patients with severe obstetric complications (gestational hypertension, preeclampsia); 4. Predicted high risk factors of postpartum hemorrhage (placental abnormalities, macrosomia, uterine fibroids, postpartum uterine inertia and history of hemorrhage), congenital and acquired coagulation dysfunction, thrombocytopenia (platelet count < 100 x 10 ^ 9).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxytocin effective dose in 50% of parturients (ED50) for adequate uterine tone;Oxytocin effective dose in 90% of parturients (ED90) for adequate uterine tone;Oxytocin dose;estimated blood loss;requirements for additional uterotonic agents;Maternal adverse effects;Uterine tone score; | — |
Countries
China
Contacts
Public ContactChangna Wei
Jiaxing maternal and Child Health Hospital
Outcome results
None listed