Patients undergoing elective cesarean section
Conditions
Interventions
0IU oxytocin group:Oxytocin I.V. bolus
0.25IU oxytocin group:Oxytocin I.V.bolus
0.5IU oxytocin group:Oxytocin I.V.bolus
1IU oxytocin group:Oxytocin I.V.bolus
3IU oxytocin group:Oxytocin I.V.bolus
5IU oxytocin group:Oxytocin I.V.bolus
Sponsors
Jiaxing Maternity and Child Health Care Hospital (Women and Children Affiliated Hospital, Jiaxing University)
Eligibility
Sex/Gender
Female
Age
35 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. ASA I - II patients, aged 35-50 years; 2. Patients with singleton pregnancy; 3. Patients with scar uterus; 4. Patients undergoing elective cesarean section; 5. Patients with transverse abdominal incision; 6. Patients with hemianesthesia; 7. Anesthesia plane T4-T6 patients.
Exclusion criteria
Exclusion criteria: 1. Pregnant women entering the stage of labor; 2. Pregnant women with premature rupture of amnion; 3. Pregnant women with oxytocin allergy; 4. Patients with severe obstetric complications (gestational hypertension, preeclampsia); 5. Pregnant women with predicted high risk factors of postpartum hemorrhage (placental abnormalities, macrosomia, uterine fibroids, postpartum uterine inertia and history of hemorrhage); 6. Patients with congenital and acquired coagulation dysfunction; 7. Patients with thrombocytopenia (platelet count < 100 x 10 ^ 9).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxytocin effective dose in 50% of parturients (ED50) for adequate uterine tone;Oxytocin effective dose in 90% of parturients (ED90) for adequate uterine tone;Oxytocin dose;requirements for additional uterotonic agents;Uterine tone score;estimated blood loss;Side effect; | — |
Countries
China
Contacts
Public ContactChang'na Wei
Jiaxing maternal and Child Health Hospital
Outcome results
None listed