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Canceled by the investigator. The expression of N/OFQ in elderly patients with coronary heart disease and its correlation with perioperative adverse cardiovascular events

The expression of N/OFQ in elderly patients with coronary heart disease and its correlation with perioperative adverse cardiovascular events

Status
Unknown
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000038886
Enrollment
Unknown
Registered
2020-10-09
Start date
2021-01-01
Completion date
Unknown
Last updated
2022-10-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular diseases

Interventions

normal control group:Nil
CHD-L group:Nil
CHD-M group:Nil
CHD-S group:Nil

Sponsors

Jinhua Hospital Affiliated to Medical College of Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients who signed the informed consent; 2. Patients aged 65-80 years old; 3. Patients with ASA grade II-III; 4. Patients with BMI of 19-27 kg / m2; 5. Coronary heart disease and non coronary heart disease patients who are scheduled for elective general anesthesia surgery.

Exclusion criteria

Exclusion criteria: One of the following situations was not included in this study: 1. Patients with recent myocardial infarction (within 6 months); 2. Unstable angina pectoris; 3. Patients with a history of congenital heart disease; 4. Patients with history of cardiac surgery; 5. Patients with frequent ventricular or atrial premature beats, atrial fibrillation, heart conduction diseases and other serious arrhythmias; Severe liver and kidney diseases; 7. Patients taking antiarrhythmic drugs in recent one week; 8. Patients with temporary or permanent pacemaker implantation.

Design outcomes

Primary

MeasureTime frame
Perioperative adverse cardiovascular events;N/OFQ;cTnI;—

Secondary

MeasureTime frame
Dosage of vasoactive drugs;—

Countries

China

Contacts

Public ContactChang Xiong

Jinhua Hospital Affiliated to Medical College of Zhejiang University

xiongchang811@163.com+86 17888299176

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026