Dilated cardiomyopathy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or older and able to give written informed consent; 2. New-Onset DCM; 3. Clinically stable without a need for intravenous diuretic, vasoactive or inotropic therapy.
Exclusion criteria
Exclusion criteria: 1. Diagnosed with acquired dilated cardiomyopathy such as alcoholic cardiomyopathy, perinatal cardiomyopathy, tachycardia induced cardiomyopathy, etc.; 2. Severe and untreated or untreatable hypertension; 3. Severe CAD defined as a stenosis of > 70% in main coronary artery, or ischemia or a past history of myocardial infarction revealed by non-invasive modalities, or a history of CABG, coronary stent implement, AMI or unstable angina; 4. Structural heart disease, e,g., primary valvular disease, congenital heart disease; 5. Other systemic diseases that may affect the structure and function of the heart, such as hyperthyroidism, hypothyroidism, amyloidosis, pheochromocytoma, systemic lupus erythematosus, Behcet's disease, etc.; 6. Malignancy, severe infection, severe liver or kidney disease, or with an expected survival of less than 1 year; 7. Pregnant; 8. Claustrophobia; 9. Reluctance to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left ventricular ejection fraction;Left ventricular end-diastolic dimension;SEN, SPE, ACC, AUC of ROC, PPV, NPV; | — |
Secondary
| Measure | Time frame |
|---|---|
| NT-proBNP;Metabolic marker; | — |
Countries
China
Contacts
West China Hospital, Sichuan University