The mechanism research of transcutaneous electrical stimulation of auricular acupuncture points in patients with mild cognition impairment

The mechanism research of the three networks on mild cognition impairment utilizing transcutaneous electrical stimulation of auricular acupuncture points

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000038868

Enrollment

Unknown

Registered

2020-10-08

Start date

2020-10-16

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild cognition impairment

Interventions

transcutaneous electrical stimulation of auricular acupuncture points:transcutaneous electrical stimulation of auricular acupuncture points on vagus nerve

transcutaneous electrical stimulation of auricular acupuncture points out of vagus nerve:transcutaneous electrical stimulation of auricular acupuncture points out of vagus nerve

normal control:no intervention

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.At least half a year of local residence at the time of investigation); 2.Han Nationality; 3.Right-handed.

Exclusion criteria

Exclusion criteria: 1.Nervous system diseases: cerebrovascular disease, encephalitis, brain tumor, brain trauma, epilepsy, Parkinson's disease and other neurological diseases that lead to cognitive decline; 2.Metabolic diseases: anemia, thyroid dysfunction, folic acid and vitamin B12 deficiency lead to cognitive decline; 3.Severe mental illness, such as severe depression 4.History of gas poisoning; 5.History of general anesthesia; 6.Dementia; 7.Acute or serious life-threatening illness; 8.Patients who have severe vision, hearing or language problems and can not complete neuropsychological assessment.

Design outcomes

Primary

Measure	Time frame
Montreal cognitive assessment, MOCA-B;	—

Secondary

Measure	Time frame
AVLT-H;STT-A&B;AFT;BNT;fMRI;EEG;PSQI;HAMD;HAMA;	—

Countries

China

Contacts

Public ContactLei Wang

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences

tommyadison123@163.com+86 10 64089407

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026