coronary artery disease
Conditions
Interventions
Gold Standard:Clinical outcomes
Index test:A 
prediciton 
model 
based 
on 
markers 
and 
blood 
for 
the 
risk 
of 
Sponsors
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. CAD group: coronary angiography showed at least one coronary artery or its main branch with diameter stenosis >= 50%, which was definitely diagnosed as coronary atherosclerotic heart disease (CAD); 2. Non CAD group: Patients with no previous history of CAD have no symptoms such as chest pain, chest distress, palpitation or shortness of breath after activity in the near future, and no evidence of CAD has been found through biochemical and ECG tests.
Exclusion criteria
Exclusion criteria: 1. Patients over 80 years old; 2. Pregnant or nursing patients; 3. Patients with acute coronary syndrome, acute heart failure or serious arrhythmia in the past 1 month; 4. Patients with infectious or non infectious inflammation in recent 1 month; 5. Patients with structural heart disease or cardiomyopathy such as valvular heart disease, atrial / ventricular septal defect; 6. Patients with serious hepatorenal insufficiency, thyroid disease, malignant tumor and hematological system disease; 7. Patients who had major surgery or suffered severe trauma in recent 2 months; 8. Patients who have used lipid-lowering drugs, antioxidants, glucocorticoids or non steroidal anti-inflammatory drugs in recent 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| inflammatory markers (hsCRP, ESR, MCP-1 and IL-6);blood lipid profile (HDL-C, TC, TG, apo A1, apo B?Lp(a));lipid subfractions (HDL2-C and HDL3-C);SEN, SPE, AUC, Z statistics, NRI, IDI; | — |
Countries
China
Contacts
Public ContactYuling Zhang
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Outcome results
None listed