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Can aerosol inhalation of ketamine reduce postpartum depression

Preventive treatment of postpartum depression by aerosol inhalation of ketamine

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000038855
Enrollment
Unknown
Registered
2020-10-07
Start date
2020-12-01
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum depression

Interventions

ketamine Group :50mg of ketamine was diluted into 10ml for atomization inhalation
control group:atomization inhalation of 10ml water for injection

Sponsors

Department of Anesthesiology, Chenzhou First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: The patients were 20-45 years old, ASA I-II grade, and planned to undergo cesarean section in the operating room under the assistance of anesthesia. The included criteria were clear consciousness, good communication and understanding of postpartum depression related complications. The depression score of the pregnant women by the preoperative depression scale (EPDS) was depression tendency (>=12 points).

Exclusion criteria

Exclusion criteria: The diagnosis of preeclampsia or toxic eclampsia puerpera; puerpera rejection; placenta previa or placental implantation; massive bleeding during the operation, the amount of bleeding more than 1000 ml; amniotic fluid embolism and other serious complications.

Design outcomes

Primary

MeasureTime frame
Depression score;

Secondary

MeasureTime frame
Family satisfaction;Postoperative nausea and vomiting;Postoperative pain score;Press times of patient controlled intravenous analgesia pump;

Countries

China

Contacts

Public ContactZhang Zhiming

Chenzhou First People's Hospital

Otc0735@163.com+86 13875555649

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026