Sevoflurane and propofol combined with rectus sheath nerve block in the operation of open rectal cancer
Conditions
Interventions
Sevoflurane combined with rectus sheath:Anesthesia was maintained by sevoflurane + remifentanil + dexmedetomidine + muscle relaxant cis-type atracurium pump injection
Propofol combined with rectus sheath:Anesthesia was maintained by propofol + remifentanil + dexmedetomidine + muscle relaxant cis atracurium pump injection
Sponsors
Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Sign the informed consent; 2. Aged 40-75 years; 3. ASA grade I~III; 4. to choose a period of open surgery for rectal cancer patients.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to regional blocking techniques (allergic to local anesthetics, peripheral infection at the puncture site and coagulation disorders); 2. A history of pain reliever dependence; 3. Patients with dementia or severe cognitive impairment; 4. Any cerebrovascular accident occurred within 3 months, such as stroke, transient ischemic attack (TIA), etc.; 5. Any communication difficulty.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative opioid demand; | — |
Secondary
| Measure | Time frame |
|---|---|
| The dosage of anesthetic drugs, vasoactive drugs and the amount of liquid in and out during the operation;Intraoperative hemodynamic fluctuation;The incidence, duration and occurrence time of postoperative delirium;The patient's recovery time, extubation time and in and out PACU time;Postoperative analgesic drug dosage and resting and exercise pain score at each follow-up time point (NRS score, 0-10);Number of analgesic pump compressions and effective number of analgesic pump compressions at 24h and 48h postoperatively;Postoperative major organ complications and length of stay;30-day postoperative mortality (telephone follow-up); | — |
Countries
China
Contacts
Public ContactXu Guanghong
Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed