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Application of abdominis sheath nerve block combined with general anesthesia in open radical resection of rectal cancer based on surgical incision

Application of abdominis sheath nerve block combined with general anesthesia in open radical resection of rectal cancer based on surgical incision

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000038844
Enrollment
Unknown
Registered
2020-10-06
Start date
2020-10-16
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Application of different nerve tissues combined with general anesthesia in open rectal cancer surgery

Interventions

Rectus abdominis sheath combined with general anesthesia:Surgical incision was performed to guide rectus sheath blockade under ultrasound (0.33% ropivacaine 30ml twice). Propofol, dexmedetomidine and
Transverse abdominal muscle membrane block combined with general anesthesia group:Bilateral transverse ventral myofilm block (0.33% ropivacaine, 30ml). Propofol, dexmedetomidine and remifentanil pump

Sponsors

Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Sign the informed consent; 2. Aged 40-75 years; 3. ASA grades I~III; 4. Patients who plan to undergo open surgery for rectal cancer.

Exclusion criteria

Exclusion criteria: 1. Patients with contraindications to the regional block technique (allergy to local anesthetic, infection around the puncture site and coagulation disorders); 2. A history of dependence on painkillers; 3. Patients with dementia or severe cognitive dysfunction; 4. Any cerebrovascular accident occurred within 3 months, such as stroke, transient ischemic attack (TIA), etc.; 5. Any poor communicator.

Design outcomes

Primary

MeasureTime frame
Intraoperative opioid demand;—

Secondary

MeasureTime frame
During the operation, the dosage of anesthetic drugs and vasoactive drugs, the amount of liquid in and out;Intraoperative hemodynamic fluctuation;Wake time, extubation time and PACU time;Dosage of additional analgesics and score of resting and exercise pain at each time point of postoperative follow-up (NRS score, 0-10);The number of analgesic pump presses and effective times 24h and 48h after operation;The incidence, duration and duration of postoperative delirium;Major postoperative complications and hospital stay;Mortality at 30 days after surgery (telephone follow-up);—

Countries

China

Contacts

Public ContactXu Guanghong

Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University

xuguanghong2004@163.com+86 13856949535

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026