Mild cognitive impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the MCI diagnostic criteria; 2. MOCA score < 26 points ; 3. Activities of Daily Living scale (ADL) score < 18 points; 4. The General Decline Scale (GDS) level was 2-3; 5. Between the ages of 60 and 75 years. F. No regular exercise in the last six months; G. Right handed; H. Have certain reading comprehension and communication skills, can cooperate to complete the scale evaluation; I. Informed consent and voluntary participation.
Exclusion criteria
Exclusion criteria: 1. Patients with hypertension whose blood pressure could not be controlled (systolic blood pressure greater than 160 mmHg or diastolic blood pressure greater than 100 mmHg); 2. History of alcohol and drug abuse; 3. Other reasons, such as severe anxiety, depression, drugs, poisoning, cerebrovascular disease caused by cognitive impairment; 4. The subjects with mental history (such as personality disorder, schizophrenia, etc.), or severe aphasia and visual impairment, or severe organ failure, myocardial infarction, coronary heart disease, musculoskeletal system diseases, sports contraindications, color blindness and low education level, etc. could not cooperate with the test; 5. Contraindications of MRI examination such as removable denture and cardiac pacemaker, taking opioids, benzodiazepines and other drugs that affect brain imaging; 6. Other researchers who are taking part in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MOCA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Memory function assessment;Attention assessment;Executive function assessment;Quality of life assessment;MRI scanning;Analysis of cortical nerve activity;Detection of Cognitive related factors in Peripheral Blood; | — |
Countries
China
Contacts
Fujian University of Traditional Chinese Medicine