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Study on the mechanism of endovascular therapy combined with acupuncture to improve the daily status of thin endometrial transplantation

Based on AMPK-MTOR signaling pathway, the mechanism of intracavitary physiotherapy combined with acupuncture to repair thin endometrium was studied

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000038834
Enrollment
Unknown
Registered
2020-10-05
Start date
2020-10-09
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thin endometrium

Interventions

Sponsors

The Hospital Affiliated of Shandong University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Patients with infertility and thin endometrium who have failed 1 or more times after IVF-ET transplantation; 2. Aged 25-40 years; 3. No history of uterine cavity operation in recent three months; 4. Basic endocrine of nearly three months is roughly normal; 5. Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Intrauterine adhesions (Asherman syndrome), endometrial tuberculosis and other organic injuries, uterine dysplasia; 2. No embryos of high quality were transplanted; 3. Patients with endometrial thickness < 6mm on the day of endometrial transformation; 4. Estrogen treatment contraindications; 5. Anemia, hyperthyroidism, tuberculosis and other serious chronic wasting diseases; 6. With serious primary diseases of the heart, liver, kidney, etc.; 7. Intelligent disorder, mental patients and other patients do not cooperate with treatment.

Design outcomes

Primary

MeasureTime frame
Endometrial homologous frame gene (HOXA-10) protein;Uterine artery blood flow index;Endometrial thickness;mTOR RNA;

Countries

China

Contacts

Public ContactConghui Pang

The Hospital Affiliated of Shandong University of Traditional Chinese Medicine

pangpangking@163.com+86 18905411211

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026