Efficacy evaluation of dexmedetomidine sole or combined butorphanol in improving post-ICU syndrome in patients undergoing cardiac surgery

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000038810

Enrollment

Unknown

Registered

2020-10-03

Start date

2020-11-01

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiac disease

Interventions

Dexmedetomidine+butorpha group:Dexmedetomidine+butorphanol

Control group:placebo

Dexmedetomidine group:Dexmedetomidine

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1. Patients unergoing Cardiac surgery; 2. Patients planned to admit to ICU; 3 Older than 18 years; 4. Sign informed Consent.

Exclusion criteria

Exclusion criteria: 1. Patients undergoing emergency surgery; 2. Preoperative cognitive impairment or physical movement disorder; 3. Allergy to medication; 4. Patients participating in other drug trials.

Design outcomes

Primary

Measure	Time frame
PICS incidence;	—

Secondary

Measure	Time frame
anxiety;cognitive impairs;physical impairs;Hospitalization;Stay in ICU;mortality in 6 months after discharge;blood routine;	—

Countries

China

Contacts

Public ContactTan Qi

Shandong Province Hospital

deepblue1229@163.com+86 18753157303

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026