The effects of bFGF on traumatic optic neuropathy after ETOCD

Exploring the effects of bFGF on visual functional recovery for the patients with traumatic optic neuropathy after ETOCD

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000038724

Enrollment

Unknown

Registered

2020-09-29

Start date

2020-09-29

Completion date

Unknown

Last updated

2020-12-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic optic neuropathy

Interventions

bFGF:ETOCD surgery followed by bFGF organism protein sponge

ETOCD only:only ETOCD surgery

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult subjects (male or female>=18 years old); Diagnosis with traumatic optic neuropathy (including direct traumatic optic neuropathy and indirect traumatic optic neuropathy); Acute visual loss followed head or facial trauma within one week; The visual acuity of injured eye better than light sense; The visual acuity without improved after corticosteroid impulse therapy two days; Informed consent signed.

Exclusion criteria

Exclusion criteria: Operational contraindications regarding to ETOCD; Severe concomitant life-threatening injury; Chronic infections of sinu; Postoperative secondary infection in Sphenoid sinus; Currently receiving an investigational drug or device.

Design outcomes

Primary

Measure	Time frame
Visual Acuity;	—

Secondary

Measure	Time frame
nerve fiber thickness of retina;visual field;	—

Countries

China

Contacts

Public ContactWencan Wu

The eye hospital of Wenzhou Medical University

wuwencan118submit@163.com+86 0577 00068959

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026