Effects of perioperative goal-directed fluid therapy combined with the deep neuromuscular block on laparoscopic colorectal surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000038699

Enrollment

Unknown

Registered

2020-09-29

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-12-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer patients

Interventions

A?:PTC1-2

B?:moderate neuromuscular block

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Adult patients between 18 to 65 years old, who undergo elective laparoscopic colorectal resection surgery and had the American Society of Anesthesiologists (ASA) physical status classification of I–II, were assessed for eligibility.

Exclusion criteria

Exclusion criteria: 1. inability to provide informed consent; 2. a neuromuscular disease or personal history or family history of malignant hyperthermia; 3. a serious heart, kidney, or liver condition; 4. previous colorectal surgical history; 5. allergies to medication to be used during anaesthesia; 6. body mass index(BMI)=35 kg/m2; 7. both hands cannot recept monitor; 8. arrhythmia.

Design outcomes

Primary

Measure	Time frame
SRS score;Hemodynamic index;Blood gas analysis index;Recovery Time;VAS;TNF-alpha;IL-6;IL-8;CRP;	—

Secondary

Measure	Time frame
postooperative hospital stay;airway pressure;pneumoperitoneum pressure;	—

Countries

China

Contacts

Public ContactZheng Lidong

Liu'an Affiliated Hospital of Anhui Medical University

zld801@163.com+86 13965490768

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026