Dry eye
Conditions
Interventions
dry eye group:30 minutes of running
normal control group:30 minutes of running
Sponsors
The Second Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Men and women are not limited, ages 20-50, all agree to participate in this study and sign an informed consent; 2. Patients diagnosed as dry eye according to the Tear Film and Ocular Surface Society (TFOS) Dry Eye Workshop(DEWS) II.
Exclusion criteria
Exclusion criteria: 1. Patients with previous ocular surface diseases such as allergic conjunctivitis; 2 .Patients with Sjogren's syndrome; 3. Patients with alterations in the lacrimal drainage system such as punctal occlusion; 4. Patients who used treatments for Dry Eye Disease within the last month; 5. patients who used contact lenses within the past month; 6. A history of ocular trauma or surgery within one year; 7. People with serious systemic diseases and are not suitable for strenuous exercise.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Schirmer I test;Best corrected visual acuity;tear meniscus height,TMH;noninvasive tear film break-up time, NIBUT;lipid layer thickness of the tear film (LLT);partial blinking rate (PBR);ocular surface disease index, OSDI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lactoferrin;metallomatrix protease9, MMP-9;IL-6;8-hydroxy-2'-deoxyguanosine,8-OHdG;OAHFA;MUC5AC; | — |
Countries
China
Contacts
Public ContactRongdi Yuan
The Second Affiliated Hospital of Army Medical University
Outcome results
None listed