knee osteoarthritis
Conditions
Interventions
high dose group:cocktail analgesic containing 3 ml of compound betamethasone
conventional dose group:cocktail analgesic containing 1 ml of compound betamethasone
control group:cocktail analgesic without compound betamethasone
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for knee osteoarthritis; 2. American Society of Anesthesiologists (ASA) physical status I-II; 3. Scheduled for unilateral total knee arthroplasty; 4. Patients aged 50~80 years old.
Exclusion criteria
Exclusion criteria: 1. patients with major psychological problems, a history of mental illness or speech impairment; 2. Diabetic patients with poor blood glucose control (arbitrary fasting blood glucose >8mmol/L), major cardiovascular diseases, liver and kidney dysfunction, history of gastric ulcer, and disorder of coagulation function; 3. patients with a history of alcohol, drug or drug abuse; 4. those who cannot successfully complete the rehabilitation plan due to central or peripheral neuromuscular defects; 5. Allergy to any of the experimental drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| one-minute walk test;thigh circumference around knee;escue analgesia and adverse event;Inflammatory markers and blood glucose level; | — |
Contacts
Public ContactDa Guo
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed