PHOTOAGING
Conditions
Interventions
low-energy group:low-energy Nd: YAG1064-nm laser
high-energy group:high-energy Nd: YAG1064-nm laser
Sponsors
Hospital for Skin Diseases (Institute of Dermatology), Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 35 to 70 years male or female; 2. Patients with Fitzpatrick skin type III-V; 3. Patients with facial photoaging; 4. Patients who agree to take pictures of the treatment area during the research and use it for scientific, educational or other purposes; 5. Patients who have fully understood the study before signing the study and voluntarily signed informed consent, and can complete all follow-up patients in accordance with the expected treatment procedure
Exclusion criteria
Exclusion criteria: 1. Active skin lesions on the face or symptoms of systemic infection; 2. Skin lesions such as melasma, brown-blue mole, and Ota mole on the face; 3. Pregnant and lactating women; 4, Recent sun-burn history; 5. Patients with a previous history of photosensitivity, who have taken drugs known to increase light sensitivity in the past 6 months; 6. Patients taking isotretinoin orally during the 12 months before the initial treatment; 7. In the past 3 months, the face has received surgical treatment including: minimally invasive, filling, injection, plastic surgery or ultraviolet light treatment, strong pulsed light, laser, radio frequency treatment 8. Patients with previous history of squamous cell carcinoma or melanoma; 9. The investigator believes that the subject has poor compliance or other organic diseases and is not suitable to participate in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Global Photoaging Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| melanin index;Global Aesthetic Improvement Scale;Pain Visual Analogue Scale;Patient's satisfaction rate;Transeipdermal water loss(TEWL); | — |
Countries
China
Contacts
Public ContactLING TONG
Hospital for Skin Diseases (Institute of Dermatology), Chinese Academy of Medical Sciences
Outcome results
None listed