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Lidocaine ultrasonic nebulization inhalation combined with tracheal tube coating inhibits the stress response of double-lumen tube intubation and extubation

Lidocaine ultrasonic nebulization inhalation combined with tracheal tube coating inhibits the stress response of double-lumen tube intubation and extubation

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000038659
Enrollment
Unknown
Registered
2020-09-29
Start date
2020-09-27
Completion date
Unknown
Last updated
2020-12-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chest disease

Interventions

blank:NS
group b:Lidocaine ultrasonic nebulization
group c:Lidocaine ultrasonic atomization combined with lidocaine cream application

Sponsors

Xuzhou Mining Group General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients with ASA grade I ~ II, 2. Patients aged 18-65 years, 3. Patients with body mass index (BMI) of 18-25kg / m2

Exclusion criteria

Exclusion criteria: 1. Patients with drug allergy history; 2. Patients with history of cardio pulmonary cerebrovascular diseases; 3. Patients with difficult airway; 4. Patients with chronic pain; 5. Patients with chronic history; 6. Patients who take medicine for a long time; 7. Patients with history of esophageal and gastric diseases; 8. Patients with endocrine diseases.

Design outcomes

Primary

MeasureTime frame
The incidence of sore throat in the sixth hour after surgery;

Secondary

MeasureTime frame
Incidence of sore throat at 0, 1, 12 hours after extubation;BP;HR;SPO2;blood sugar;Catecholamine plasma concentration;

Contacts

Public ContactMingjian Kong

Xuzhou Mining Group General Hospital

mjkong@126.com+86 17751991669

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026