thyriod goiter
Conditions
Interventions
Remifentanil group (R group):TCI 2.0ng/ml remifentanil during extubation
Lidocaine group (L group):Lidocaine 2% around the outer surface of endotracheal tube cuff during extubation
Sponsors
Guangdong Provincial Hospital of Tradition Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) 18-65 years old female; 2) ASA grade I-II; 3) Patients with thyriod surgery who are to be operated on under general anesthesia by endotracheal intubation; 4) Obtain the informed consent of the patient and/or the legal guardian and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) Use the NIM standard reinforced EMG endotracheal tube & NIM contact reinforced EMG endotracheal tube for nerve monitoring; 2) Mental disorders, inability to communicate, difficult airways, high perioperative risk of reflux aspiration; 3) A history of chronic respiratory disease (such as chronic obstructive pulmonary disease or asthma), recent respiratory infection, chronic cough, smoking; 4) Serious cardiovascular, liver, or kidney disease; 5) Prior laryngeal or tracheal surgery, local anesthetic allergy, and treatment with beta blockers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cough grading system; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure and heart rate;the Richmond Agitation-Sedation Scale (RASS);Critical-Care Pain Observation Tool;Sedation Grading System;Visual Analogue Scale; | — |
Countries
China
Contacts
Public ContactPing Li
Department of Anesthesiology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, P. R. China
Outcome results
None listed