Predictive value of Pax1 methylation detection in cervical lesions

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000038633

Enrollment

Unknown

Registered

2020-09-26

Start date

2020-01-01

Completion date

Unknown

Last updated

2020-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical cancer

Interventions

Gold Standard:The gold standard is histopathological diagnosis

Index test:Pax1&#32

methylation&#32

detection

Eligibility

Sex/Gender

Female

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) Aged 18 to 65 years old; 2) Gynecological examination suspected of cervical lesions; 3) HPV16 or 18 positive; 4) The cervical cytology showed LSIL and above, ASCUS was positive with high risk HPV.

Exclusion criteria

Exclusion criteria: 1) Pregnancy patients; 2) Acute inflammation of cervix vaginalis; 3) There are contraindications, such as severe cardiovascular and cerebrovascular diseases and hematopoietic system dysfunction.

Design outcomes

Primary

Measure	Time frame
Methylation of Pax1 gene;Sensitivity;Specificity;Accuracy;PPV;NPV;AUC of ROC;	—

Countries

China

Contacts

Public ContactXie Ya

The First Affiliated Hospital of Zhengzhou University

xieya838@126.com+86 13783550438

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026