Chronic obstructive pulmonary disease
Conditions
Interventions
Control group, COPD group, non-smoking lung cancer group, COPD with lung cancer group:Bronchoalveolar lavage via bronchoscope
Sponsors
Department of Respiratory Medicine, the first affliated hospital, Navy Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients with lung cancer confirmed by pathology or cytology 2. Patients aged 18 to 75 years agreed to participate in the study and signed informed consent; 3. Smoking history>=20 pack years (>=400years); 4. FEV1/FVC<0.7 after bronchodilation test; 5. Patients agreed to participate in the study and signed informed consent; 6. No severe heart, liver, kidney or brain complications.
Exclusion criteria
Exclusion criteria: 1. Those who can not complete the bronchial examination; 2. Severe heart, liver, kidney, brain and other complications; 3. Patients with active pulmonary infection within 1 month; 4. Refuse to sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Phenotype of macrophages in bronchoalveolar lavage fluid;Exosomes of alveolar macrophages; | — |
Countries
China
Contacts
Public ContactJingxi Zhang
Department of Respiratory Medicine, the first affliated hospital, Navy Medical University
Outcome results
None listed