Multimodal analgesia versus traditional opiate based analgesia

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000038585

Enrollment

Unknown

Registered

2020-09-24

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac-Vascular Surgery

Interventions

experimental group:Multimodal analgesia

control group:traditional opiate based analgesia

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 80years; 2. American Society of Anaesthesiologists (ASA) Score II-III; 3. Body mass index (BMI) of 18 to 31; 4. Elective on-pu mp cardiac surgery through median sternotomy; 5. Written informed consent.

Exclusion criteria

Exclusion criteria: 1. Participating in other clinical trials at the same time; 2. Patients who are unable to cooperate or communicate; 3. Deep Hypothermic Circulatory Arrest; 4. Patients undergoing secondary surgery; 5. Patients with liver, kidney or coagulation insufficiency before operation; 6. Known abusers of alcohol, drugs or narcotics; 7. Women who are pregnant or nursing; 8. expected survival less than 24 h.

Design outcomes

Primary

Measure	Time frame
Analgesic effect;	—

Secondary

Measure	Time frame
Additional opioid consumption;postoperative delirium;Incidence of acute kidney injury;PONV;Dysglycemia;mechanical ventilation time;ICU stay;Hospital stay;The systemic immune-inflammation index;	—

Countries

China

Contacts

Public ContactLin Jin

Zhongshan Hospital, Fudan University

jin.lin@zs-hospital.sh.cn+86 13917131195

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026