asymptomatic hyperuricemia
Conditions
Interventions
experimental group:Fuling-Zexie Decoction
control group:placebo
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged between 18-75 years; 2. Patients who meet the diagnosis of asymptomatic hyperuricemia; 3. Patients who meet the dampness syndrome inclusion criteria; 4. Patients who sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Secondary hyperuricemia population, for instance, secondary to malignancy, hemopathy, nephropathy, chronic intoxication; 2. History of alcoholism without abstinence in recent 3 months; 3. Had one or more attacks of gout arthritis in the past; 4. Received urate-lowing drugs or drugs that may increase serum uric acid in recent 4 weeks, such as antituberculotic drugs, low dose aspirin, Loop diuretics and thiazide diuretics and blood pressure medications containing diuretics, niacin, large dosage of vitaminC, chemotherapeutic drugs and cyclosporin; 5. Pregnancy and lactation population, or has possibility of conception but failure to use effective contraception; 6. Alanine aminotransferase or aspartate aminotransferase or creatinine 2 times or more than the normal value; 7. Combined with serious organic lesions, mental disorders or other reasons can not cooperate with treatment; 8. Allergic or ineffective to the test drug ingredients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the decrease in serum uric acid; | — |
Secondary
| Measure | Time frame |
|---|---|
| Chinese syndrome score;measurement of the Chinese channel and tongue diagnosis;Glomerular filtration rate;Urinary ß2 microglobulin;uric acid excretion fraction;Incidence rate of complications, such as gout, hyperlipemia, cardiovascular events, diabetes, etc.;Ultrasound of double ankles and the first metatarsophalangeal joints;blood?urine metabolite;Inflamation index: hsCRP, TNF-a, IL-6, IL-8; | — |
Countries
China
Contacts
Public ContactXiaohog He
Guangdong provincial hospital of Chinese Medicine
Outcome results
None listed