FindTrial
Sign In

Correlation analysis of irisin level and Klotho protein level in cerebrospinal fluid of stroke patients

Mechanism of irisin alleviating cognitive dysfunction after stroke through regulating Klotho protein

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000038569
Enrollment
Unknown
Registered
2020-09-24
Start date
2020-10-12
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

control:No
Acute:No
Recovery:No

Sponsors

Zhongnan Hospital of Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with acute ischemic stroke diagnosed by CT / MRI

Exclusion criteria

Exclusion criteria: 1. intracerebral hemorrhage, malignant tumor, sarcopenia, liver insufficiency and renal insufficiency (creatinine > 1.5 mg/dl), febrile disorders and autoimmune diseases; intolerance or allergy to alcohol consumption, regular use of sedative/hypnotics; 2. without informed consents, lost blood samples, or current use of metronidazole or warfarin, and psychiatric illness; 3. lost or give up during the follow-up.

Design outcomes

Primary

MeasureTime frame
irisin;Klotho;—

Countries

China

Contacts

Public ContactJianjuan Ke

Zhongnan Hospital of Wuhan University

wb002405@whu.edu.cn+86 13517232805

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026