Knee osteoarthritis
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Henan University of CM
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Male or female, aged 45–75 years; 2. Following the diagnostic criteria of knee osteoarthritis, and Right-handed; 3. Good compliance and willing to cooperate with the research; 4. Radiologic confirmation of knee osteoarthritis (Kellgren–Lawrence grade I-III); 5. The informed consent form was signed by the patient or by their immediate family members.
Exclusion criteria
Exclusion criteria: 1. Complicated with other knee joint diseases, such as tuberculosis, tumor, rheumatism and rheumatoid arthritis; 2. Complicated with sprain, contusion or other trauma, foot deformity, pain and other diseases affecting normal walking; 3. Patients with severe cardiovascular disease, damage of liver and kidney function, immune deficiency, diabetes mellitus, and blood disease; 4. Severe drug and alcohol dependence, mania or schizophrenia; 5. Patients with obvious headache, migraine, dysmenorrhea and other chronic pain diseases, history of head trauma; 6. Be insensitive to pain due to advanced diabetes, neuropathy or use of strong painkillers; 7. have knee pain caused by radiculopathy/herniation of an intervertebral disc; 8. Have a history of prolotherapy, hyaluronic acid injections or corticosteroids injections within 3 months; 9. have received acupuncture, electro-acupuncture, Tui-na therapy, massage, or physiotherapy 8 weeks prior to enrolment in the trial; 10. Have MRI contraindications such as claustrophobia, cardiac pacemaker, defibrillator, heart stenting, or intrauterine device.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster University Osteoarthritis Index scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Knee Injury and Osteoarthritis Outcome Score, KOOS;Arthritis Quality of Life Measurement Scale Simplified Scale (AIMS2-SF);Baker anxiety scale (BAI);Baker Depression scale (BDI);The pain visual analogue scale (VAS);The Chinese version of the modified Massachusetts General Hospital Acupuncture Sensation Scale (C-MMASS)The Chinese version of the modified Massachusetts General Hospital Acupuncture Sensation Scale (C-MMASS); | — |
Countries
China
Contacts
Public ContactShuai Yin
The First Affiliated Hospital of Henan University of CM
Outcome results
None listed