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Comparative study of two anti-hypertensive treatments for hypertensive emergencies

a comparative study of intravenous nitroglycerine with intravenous labetolol for treatment of hypertensive crisis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000038540
Enrollment
Unknown
Registered
2020-09-23
Start date
2020-01-01
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

A:Labetolol
B:Nitroglycerin

Sponsors

Dr Mohammad Azharuddin Malik
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Patient who after been informed of the investigational nature of this study have given written informed consent 2. Aged >=18 years; 3. SBP>=180 mm Hg and/or DBP>=120 mm Hg with evidence of acute end organ damage; 4. SBP>=220 mm Hg and/or DBP>=130 mm Hg without evidence of any acute end organ damage.

Exclusion criteria

Exclusion criteria: 1. Use of any investigational drug within 30 days; 2. Acute or Chronic liver failure; 3. Known left ventricular ejection fraction of less than 35%; 4. Acute Pulmonary edema; 5. History of obstructive airway diseases; 6. Sinus bradycardia and atrioventricular blocks; 7. Pregnant and lactation; 8. Pheochromocytoma; 9. Known allergies to any of the study drug(s).

Design outcomes

Primary

MeasureTime frame
Proportion of patients achieving treatment goals at 3 hour.;—

Countries

India

Contacts

Public ContactDr Mohammad Azharuddin Malik

Department of Cardiology, Aligarh Muslim University

malikazharuddin@gmail.com+918126320218

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026