A comparative study of myocardial protection effects in congenital heart disease with left ventricular hypertrophy: del Nido and HTK solution

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000038531

Enrollment

Unknown

Registered

2020-09-23

Start date

2020-09-15

Completion date

Unknown

Last updated

2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Left ventricular hypertrophy

Interventions

1:del Nido Cardiaplegia solution

2:HTK Cardiaplegia solution

Eligibility

Sex/Gender

All

Age

No minimum to 18 Years

Inclusion criteria

Inclusion criteria: 1. Selection for disease: Interrupted Aortic Arch,Coarctation of aorta, Aortic Stenosis, Subvalvular Aortic Stenosis, Supravalvular Aortic Stenosis. Including Patent Foramen Ovale, Ventricular Septal Defect, Atrial Septal Defect, Patent Ductus Arteriosus 2. Other Ruquirements (1) Fisrt time surgery b.Left Ventricular Hypertrophy (LVMI>95 percent of the same sex and age children); (2) Aged <=18 years.

Exclusion criteria

Exclusion criteria: (1) Combination of other complex intracardiac malformations or syndromes; (2) Operation age <34 week; (3) Operation weight<3000g; (4) Emergency operation; (5) Residual obstruction and shunt.

Design outcomes

Primary

Measure	Time frame
Cardiac Index;	—

Secondary

Measure	Time frame
Creatine Kinase;cTnT I;IL-6;IL-8;IL-10;IS;Number of arrhythmia during arrest;hospital days;ICU stay;	—

Countries

China

Contacts

Public ContactZhongqun Zhu

Shanghai Children’s Medical Center, Shanghai Jiaotong University School of Medicine

zhuzhongqun@scmc.com.cn+86 18930830767

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026