Lung cancer
Conditions
Interventions
Group 1:Total intravenous anesthesia
Group 2:Intravenous-inhalation compound general anesthesia
Sponsors
Cancer Hospital Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 40 patients with stage I and stage II lung cancer who are planning to undergo thoracoscopic surgery, aged 18-70 years, ASA I-III grade.
Exclusion criteria
Exclusion criteria: (1) preoperative anemia: male Hb 37.5 degree C the day before surgery; (3) lungs before surgery Ventilation dysfunction; (4) Pulmonary infection, bronchial asthma or airway hyperresponsiveness before surgery; (5) Past thoracic surgery history; (6) Cardiac function above grade II; (7) Patients with hypertension, Preoperative systolic blood pressure> 140 mmHg and/or diastolic blood pressure> 90 mmHg; (8) Preoperative congenital heart disease, valvular disease, coronary heart disease, arrhythmia; (9) Central nervous system disease, history of stroke; (10) Combined with liver dysfunction and renal dysfunction; (11) history of preoperative radiotherapy and chemotherapy; (12) Postoperative diagnosis of stage III and IV lung cancer patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VEGF-c, TGF-beta, IL-6, IL-10, IFN-gama, TNF-alpha; | — |
Secondary
| Measure | Time frame |
|---|---|
| VRS at 24h and 48h after surgery; | — |
Countries
China
Contacts
Public ContactGuo Zhixing
Department of Anesthesiology, Cancer Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed