Early osteoarthritis of the knee
Conditions
Interventions
Sponsors
Wangjing Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
38 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of western or Traditional Chinese medicine for knee osteoarthritis; 2. It meets the requirements for the indications of the diagnosis and treatment technology studied; 3. Compliance with Kellgren-lawrance X-ray classification level 0, Level I and Level II; 4. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who do not meet the diagnostic criteria and inclusion criteria for knee osteoarthritis. 2. Those who have received other relevant treatments, which may affect the effect indicators in this study. 3. Patients with life-threatening primary diseases such as cardiovascular and cerebrovascular diseases, liver and kidney diseases and mental diseases. 4. Exclude research diseases: (1) rheumatic diseases: rheumatoid arthritis, ankylosing spondylitis, etc.; (2) Infectious arthritis: joint tuberculosis, purulent arthritis, etc.; (3) Reactive arthritis: allergic arthritis, thrombocytopenic purpura arthritis; (4) Metabolic joint diseases: Kashin-beck disease, gout, etc.; (5) Intra-articular tumor; (6) Other specific joint diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC Osteoarthritis Index score;Lequesne index score;TCM clinical symptom score;Serum indexes (TGF-beta 1, BMP-2, Smad1); | — |
Countries
China
Contacts
Public ContactHongmei Zhang
Wangjing Hospital
Outcome results
None listed