Clinical study on the sugammadex for recovery of neuromonitoring in spinal surgery

ED50 of sugammadex for rapid recovery of signal of intraoperative motor evoked potentials monitoring in spinal surgery

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000038470

Enrollment

Unknown

Registered

2020-09-23

Start date

2020-10-01

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Monitoring of neurological function in spinal surgery

Interventions

sugammadex:sugammadex

Eligibility

Sex/Gender

All

Age

45 Years to 65 Years

Inclusion criteria

Inclusion criteria: Those who meet the following conditions at the same time 1. ASA class I - II subjects; 2. Subjects aged 45-65 years; 3. Patients scheduled for elective lumbar surgery need intraoperative neuroelectrophysiological monitoring. 4. Patients willing to sign informed consent.

Exclusion criteria

Exclusion criteria: Patients who met any of the following criteria were excluded: 1. Patients with expected difficult airway; 2. Patients with BMI > 27kg / m2; 3. Patients with asthma history; 4. Patients who are known to be allergic to rocuronium and salbutamol; 5. Patients with severe heart, lung, liver and kidney dysfunction; 6. Patients with neuromuscular diseases; 7. Patients with history of epilepsy; 8. Patients with implanted electrical devices (such as artificial pacemaker, cochlear implant, etc.)

Design outcomes

Primary

Measure	Time frame
Recovery time of motor evoked potentials;	—

Countries

China

Contacts

Public ContactRong Ma

The First Affiliated Hospital of Nanjing Medical University

mrongerr@163.com+86 13851561882

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026