Application of Esketamine in Induction of General Anesthesia in Neurosurgery

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000038469

Enrollment

Unknown

Registered

2020-09-23

Start date

2020-10-01

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neurosurgery

Interventions

Esketamine group:Anesthesia induction to esketamine 0.5-1 mg/kg

Remifentanil group:Anesthesia induction with Sufen 0.1-0.5 ug/kg

Eligibility

Sex/Gender

All

Age

No minimum to 64 Years

Inclusion criteria

Inclusion criteria: 1. Patients with asa1-2 grade; 2. Patients younger than 65 years old; 3. Patients with spinal cord disease, 4. Patients with intracranial benign tumor without intracranial hypertension symptoms.

Exclusion criteria

Exclusion criteria: 1. Patients with high intracranial pressure, brain stem space occupying, and patients with huge tumor > 5cm before operation; 2. Patients with poor control of hypertension; 3. Patients with intracranial malignant tumor.

Design outcomes

Primary

Measure	Time frame
Hemodynamics;	—

Secondary

Measure	Time frame
Mannitol or not;Postoperative follow-up agitation score;Hyperventilation or not;	—

Countries

China

Contacts

Public ContactGeng Qian

Sanbo Brain Hospital of Capital Medical University

515745305@qq.com+86 15910616145

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026