Patients requiring enteral nutritional support after gastrointestinal surgery
Conditions
Interventions
Group 1:NSGI
Group 2:Nutrison
Sponsors
Shanghai Tenth People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients requiring enteral nutrition support after gastrointestinal surgery; 2. Aged 18-75 years; 3. BMI 18.5-28.0 kg/m2 at admission; 4. Apache-II score = 7 days; 6. The informed consent is signed, and the questionnaire survey and follow-up need to be completed as required.
Exclusion criteria
Exclusion criteria: 1. Unable to establish enteral nutritional pathways; 2. Patients with enteral nutrition contraindications such as hemodynamic instability, gastrointestinal bleeding, postoperative acute pancreatitis, inflammatory bowel disease (Crohn's disease or ulcerative colitis), intestinal ischemia, persistent intestinal obstruction, intestinal paralysis, high flow intestinal fistula and inability to establish distal access; 3. The presence of infectious diarrhea; 4. Bone marrow or organ transplant patients; 5. Other patients with leukopenia, neutropenia, malignant blood diseases, HIV and other diseases are considered not suitable to participate in this study clinically; 6. Patients with renal insufficiency (eGFR < 60mL/min) or in need of dialysis treatment; 7. Abnormal thyroid function; 8. The patient, legal representative or guardian refuses to participate in the study; 9. Pregnant or lactating female patients; 10. Known to be allergic to any of the ingredients in the study or control product, or determined by the investigator to require dietary fiber restriction; 11. Galactosemia; 12. Expected survival <= 10 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the proportion of patients with diarrhea >=1 day; | — |
Secondary
| Measure | Time frame |
|---|---|
| The proportion of diarrhea days in the total feeding days;the proportion of patients with constipation;the proportion of patients with abdominal distension;the proportion of patients with Nausea or vomiting;change of body weight and BMI;Changes of prealbumin level before and after 5 days of enteral nutrition support after gastrointestinal surgery;Fasting blood glucose after gastrointestinal surgery;Total intake of enteral nutrient solution and total energy intake per day;Length and total costs in hospital stay;Quality of life;Number of rehospitalizations within 30 days of discharge;Changes in gut microbiota; | — |
Countries
China
Contacts
Public ContactTing Han
Shanghai Tenth People's Hospital
Outcome results
None listed