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Feasibility study of simultaneous treatment of 2-10 metastases in the lung with SBRT

Feasibility study of simultaneous treatment of 2-10 metastases in the lung with SBRT

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000038352
Enrollment
Unknown
Registered
2020-09-21
Start date
2020-10-08
Completion date
Unknown
Last updated
2020-12-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung metastasis

Interventions

1:DT: 20Gy
2:DT: 30Gy
3:DT: 40Gy
4:DT: 50Gy
5:DT: 60Gy

Sponsors

Affiliated Hospital of Guizhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Patients with malignant solid tumors (lung cancer, colorectal cancer, head and neck squamous cell carcinoma, cervical cancer) diagnosed by histopathology or cytology; (2) In patients with multiple lung metastases diagnosed by imaging (enhanced chest CT, PET-CT) or pathological examination, in principle, there are several metastases, and the diameter of a single lesion is = 70, and the expected survival period is >= 6 months; (7) There is no significant abnormality in lung function: FEV1 > 50%.

Exclusion criteria

Exclusion criteria: (1) Patients who have received pulmonary radiotherapy within one year; (2) Those who have undergone lobectomy or pneumonectomy and affected lung function; (3) Chronic lung diseases that seriously affect lung function, such as pulmonary bullae, chronic obstructive pulmonary disease, pneumoconiosis, old tuberculosis, etc.; (4) Severe lung infection or active tuberculosis; (5) There is an uncontrollable amount of pleural fluid; (6) There are any contraindications to radiotherapy and chemotherapy.

Design outcomes

Primary

MeasureTime frame
Tumor regression;Radiation lung injury;

Countries

China

Contacts

Public ContactLu Bing

Affiliated Hospital of Guizhou Medical University

lbgymaaaa@163.com+86 13809432527

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026