Correlation study of urine exosomes miRNAs and renal macrophage infiltration in IgA nephropathy patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000038337

Enrollment

Unknown

Registered

2020-09-18

Start date

2020-06-01

Completion date

Unknown

Last updated

2020-12-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IgA nephropathy

Interventions

Case series:Nil

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients who meet the diagnostic criteria of IgA nephropathy; 2. Patients aged 18-65 years; 3. Patients without other kidney diseases did not receive renal replacement therapy; 4. Patients with good general condition can take care of themselves.

Exclusion criteria

Exclusion criteria: 1. Patients under 18 years old or over 65 years old; pregnant and lactating women; female pregnancy test positive; 2. Patients with severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney, hematopoietic system, etc., or known serious diseases affecting their survival (such as cancer or AIDS), or patients with mental or legal disabilities.

Design outcomes

Primary

Measure	Time frame
Degree of macrophage infiltration;IDO quantitative;urine exosomes miRNAs semi-quantitative;	—

Secondary

Measure	Time frame
Body mass index (BMI);Serum albumin;hemoglobin;Serum creatinine;urinalysis;Exosome concentration;	—

Countries

China

Contacts

Public ContactYuan Li

Affiliated Hospital of Nantong University

yuanlint@163.com+86 13962931090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026