Epilepsy
Conditions
Interventions
Trial group:LITT treatment
Sponsors
Beijing Tiantan Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
0.5 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 6 months to 70 years old; 2. Patients who were previously diagnosed with drug-resistant epilepsy and focal seizures; 3. Patients with average seizure frequency >= 2 times / month 3 months before screening; 4. Patients with limited epileptogenic focus and suitable for surgical treatment; 5. The subjects or their guardians can understand the purpose of the trial, show adequate compliance with the trial protocol, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. MRI contraindication patients; 2. Patients with severe coagulation dysfunction; 3. Pregnant or lactating women; 4. Subjects who have participated in clinical trials of any other drugs or medical devices within 3 months before screening; 5. Patients with evidence of serious or uncontrollable systemic diseases as judged by researchers; 6. Subjects considered unsuitable for the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRI-guided LITT ablation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Seizure free rate;Seizure reduction rate;Surgical time;Postsurgical time;MMSE score;QOLIE-31, QOLIE-AD-48 scores;Instrument performance evaluation; | — |
Countries
China
Contacts
Public ContactKai Zhang
Beijing Tiantan Hospital Affiliated to Capital Medical University
Outcome results
None listed