Helicobacter pylori infection
Conditions
Interventions
empirical therapy group:esomeprazole magnesium 20 mg, furazolidone 100 mg, amoxicillin 1000 mg, and colloidal bismuth pectin 200 mg, all twice daily for 10 days
tailored therapy group:esomeprazole magnesium 20 mg, amoxicillin 1000 mg, clarithromycin 500 mg or minocyline 100 mg and colloidal bismuth pectin 200 mg, all twice daily for 10 days
Sponsors
Department of Gastroenterology, the Second Affiliated Hospital of Medical College of Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with chronic gastritis confirmed by gastroscopy were randomly selected 1. The patients aged from 18 to 70 years old were male and female; 2. HP positive patients; 3. Patients who had not received regular HP treatment before.
Exclusion criteria
Exclusion criteria: 1. Patients who had taken antibiotics,bismuth agent,PPI or H2 receptor antagonist (H2RA) 4 weeks before the study; 2. Patients with previous gastrectomy; 3. Patients with malignancy or severe comorbidity; 4. Patients who were allergic to any study medications; 5. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication rate of Helicobacter pylori infection; | — |
Secondary
| Measure | Time frame |
|---|---|
| The Antibiotic Resistance Rate of Helicobacter Pylori; | — |
Countries
China
Contacts
Public ContactQin Du
Department of Gastroenterology, The Second Affiliated Hospital, School of Medicine, Zhejiang University
Outcome results
None listed