Cirrhotic portal hypertension
Conditions
Interventions
experimental group:Laparoscopic splenectomy
Sponsors
Shunde Hospital of Southern Medical University (Shunde First People's Hospital, Foshan)
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged from 18 to 75 years old, regardless of gender; 2. Patients with liver cirrhosis complicated with portal hypertension diagnosed clinically and / or pathologically; 3. Patients with a history of esophagogastric variceal hemorrhage (melena, hematemesis, etc.) who have never received endoscopic treatment; 4. Patients with HVPG >= 16mmhg were detected after admission; 5. Patients with child Pugh grade A or B; 6. Patients with ECoG score = 60; 7. Patients who voluntarily participated in the study agreed to cooperate with the researchers in data collection and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women; 2. Patients with or suspected of liver cancer, cholangiocarcinoma and other malignant tumors; 3. Patients with severe coagulation disorders; 4. Patients with massive ascites; 5. Patients who are not suitable or willing to accept HVPG test; 6. Other situations that the researcher thinks are not suitable to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hepatic venous pressure gradient; | — |
Countries
China
Contacts
Public ContactWeidong Wang
Shunde Hospital of Southern Medical University(Shunde First People's Hospital, Foshan)
Outcome results
None listed