Effect of positive end-expiratory pressure guided by dynamic lung compliance on right heart function during abdominal laparoscopic surgery with Trendelenburg position

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000038212

Enrollment

Unknown

Registered

2020-09-13

Start date

2020-09-13

Completion date

Unknown

Last updated

2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Right heart function is impaired

Interventions

Lung dynamic compliance group: Positive end-expiratory pressure was set according to dynamic lung compliance

fixed group:Positive end-expiratory pressure was set at 4 cmH2O

Eligibility

Sex/Gender

All

Age

25 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing head down laparoscopic surgery (estimated operation time > 120min), 2. ASA I- II; 3. Patients aged 25 to 65 years old; 4. Patients who have signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with arteriovenous puncture failure; 2. Patients with failure of oesophageal ultrasound probe implantation or accidents during the implantation process; 3. Patients with intraoperative accidents (including high airway pressure, intraoperative blood loss > 25% of their own blood volume, or intraoperative monitoring of HB < 7g / L, allergy, unstable circulation, change of operation mode, etc.).

Design outcomes

Primary

Measure	Time frame
RVEDA/LVEDA;TAPSE;	—

Countries

China

Contacts

Public ContactLianhua Chen

Shanghai General Hospital

391262491@qq.com+86 13818945841

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026