Liver disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria (only when all the following criteria are met can they be included) : (1) Chronic hepatitis B patients treated with TDF; (2) Aged >= 18 years; (3) Be willing to sign the informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria (subjects are excluded from the study if they meet any of the following criteria): (1) Allergic to TAF or active ingredients; (2) Pregnant and lactating women; (3) Diagnosis of HCC within 3 months prior to enrollment; (4) Life expectancy less than 1 year; (5) Other researchers think it is not suitable to be included in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone mineral density;Renal tubular function;Glomerular filtration rate; | — |
Countries
China
Contacts
The Fifth Affiliated Hospital of Sun Yat-Sen Universit