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Study on the expression of TGF- ß 1, MMP-14, P38MAPK and VEGF in synovium of rotator cuff space of patients with frozen shoulder in different stages

Study on the expression of TGF- ß 1, MMP-14, P38MAPK and VEGF in synovium of rotator cuff space of patients with frozen shoulder in different stages

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000038181
Enrollment
Unknown
Registered
2020-09-12
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

frozen shoulder

Interventions

Grouping by stages:Nil

Sponsors

Beijing Luhe Hospital affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Shoulder pain time 3-24 months; (2) able to tolerate conservative treatment, surgical treatment and routine rehabilitation training; (3) normal joint space and humeral head shape on X-ray films of positive position of shoulder joint and outlet position of supraspinatus muscle; (4) willing to participate in this study and follow-up: be able to understand and complete the evaluation of treatment results under the guidance of doctors.

Exclusion criteria

Exclusion criteria: (1) Unwilling to participate in this study and unable to tolerate conservative treatment, surgical treatment and routine rehabilitation training: (2) diabetic patients; (3) trauma, dislocation and surgical history of shoulder joint and ipsilateral upper limb; (4) complicated with severe cardio-cerebrovascular and nervous system diseases; (5) hematological diseases and allergic to injecting drugs; (6) rheumatoid arthritis. (7) shoulder osteoarthritis and calcified tendinitis; (8) shoulder infectious disease; (9) shoulder joint MRI confirmed rotator cuff injury, glenoid labrum tear; (10) shoulder tumor patients; (11) cervical vertebra history.

Design outcomes

Primary

MeasureTime frame
transforming growth factor-ß;MMPS;VEGF;

Countries

China

Contacts

Public ContactLiu Liang

Beijing Luhe Hospital affiliated to Capital Medical University

liuliang@medmail.com.cn+86 13910295026

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026