Breast cancer
Conditions
Interventions
Case series:Nil
Sponsors
Shandong Cancer Hospital and Institute
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. For patients with stage IV HER-2 positive breast cancer confirmed by histopathology as recurrence and metastasis or inoperable at the time of diagnosis, HER-2 positive breast cancer was defined as primary or metastatic foci, and HER-2 positive tissue samples were 3 + by immunohistochemistry or + by fluorescence in situ hybridization (FISH); 2. Patients aged 18-80 years; 3. According to the response evaluation criteria in solid tumors (RECIST 1.1), patients with at least one measurable lesion; 4. The ECoG score of physical fitness was less than 2; 5. Patients with an estimated survival time of more than 3 months; 6. In patients with normal function of important organs, blood routine examination and liver and kidney function examination before chemotherapy were basically normal, without treatment contraindications.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Patients who cannot understand this study or fail to sign an informed consent form; 3. No traceable medical record available; 4. Other patients who are not suitable for this study under investigators' consideration.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression Free Survival;Adverse Events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall Survival;Objective Response Rate;Duration of Response;Clinical Benefit Rate;Quality of Life;Compliance; | — |
Countries
China
Contacts
Public ContactHuihui Li
Shandong Cancer Hospital and Institute
Outcome results
None listed