Spinal disease
Conditions
Interventions
experimental group 1:High concentration dexmedetomidine infusion
experimental group 2:Low concentration dexmedetomidine infusion
Sponsors
Department of Anesthesia,the First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing spinal surgery requiring neuroelectrophysiological monitoring under general anesthesia, 2. ASA I - III patients, 3. Patients aged 18-80 years.
Exclusion criteria
Exclusion criteria: 1. Patients with allergic history to the drugs used; 2. Patients with nerve conduction pathway injury; 3. Patients with intracranial hypertension syndrome; 4. Patients with diabetic peripheral neuropathy; 5. Patients with myasthenia gravis; 6. Patients with abnormal liver and kidney function; 7. Patients with severe circulatory and respiratory diseases; 8. Patients with mental disorders; 9. Patients with pacemaker implantation; 10. Patients with history of epilepsy; 11. Patients with skull defect; 12. Patients with hearing impairment; 13. Patients with language difficulties.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amplitude of somatosensory evoked potential;Lantency of somatosensory evoked potential;Amplitude of motor evoked potential;Lantency of motor evoked potential; | — |
Countries
China
Contacts
Public ContactXiaoning Tang
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed