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Comparative study on the effects of atrioventricular sequential pacing and minimized ventricular pacing on atrial high frequency episode, mitral regurgitation and exercise capacity in patients with sick sinus syndrome and first degree atrioventricular block

Comparative study on the effects of atrioventricular sequential pacing and minimized ventricular pacing on atrial high frequency episode, mitral regurgitation and exercise capacity in patients with sick sinus syndrome and first degree atrioventricular block

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000038149
Enrollment
Unknown
Registered
2020-09-11
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sick sinus syndrome

Interventions

Minimal ventricular pacing group:According to the baseline PR interval of patients, the paced and sensed AV interval are set, and the special function of the pacemaker is turned on. The ventricular pa
Atrioventricular sequential pacing group:Fixed paced and sensed AV intervals are set to ensure atrioventricular sequential pacing. The ventricular pacing burden is more than 90%

Sponsors

Xuzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients older than 18 years, 2. According to the ACC / AHA dual chamber pacemaker implantation guidelines, the patients are class I or class IIa indications; 3. Patients with i-degree atrioventricular block (PR >= 200ms) indicated by basic ECG; 4. Patients with normal cardiac structure were examined by ultrasonography; 5. Patients with ejection fraction > 50%.

Exclusion criteria

Exclusion criteria: 1. Patients with atrioventricular block and highly pacemaker-dependent; 2. Patients with paroxysmal or persistent atrial fibrillation; 3. Patients with structural heart disease; 4. Patients expecting life span less than one year; 5. Patients with cardiomyopathy, previous myocardial infarction, congestive heart failure, severe arrhythmia.

Design outcomes

Primary

MeasureTime frame
atrial high frequency episode;

Secondary

MeasureTime frame
vena contracta width;mitral regurgitation fraction;The Duke Activity Status Index;International Physical Activity Questionnaire;

Countries

China

Contacts

Public ContactHan Bing

Xuzhou Central Hospital

hbing777@hotmail.com+86 13505218127

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026