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The clinical study of uric acid-lowering therapy for blood pressure control in patients with prehypertension and hyperuricemia

The clinical study of uric acid-lowering therapy for blood pressure control in patients with prehypertension and hyperuricemia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000038137
Enrollment
Unknown
Registered
2020-09-11
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prehypertension

Interventions

experimental group:Febuxostat
control group:Nil

Sponsors

Deyang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: Diagnostic criteria: prehypertension - the diagnosis of hypertension in 2017 AHA was diagnosed as eh, that is, the mean value of three instant blood pressure on different days: systolic blood pressure (130 - 139mmhg (1mmhg = 0. 1333kpa) and / or diastolic blood pressure (80-89) mmHg. 1. Patients who voluntarily participate and sign informed consent form; 2. Patients aged 65-80 years, regardless of gender; 3. Subjects with uric acid level > 7Mg / ml; 4. Subjects with IMT less than 0.9 mm measured by carotid artery Doppler ultrasound; 5. Subjects with normal body mass index, blood glucose and blood lipid levels (BMI 1.04mmol/l).

Exclusion criteria

Exclusion criteria: 1. Patients older than 80 years old; 2. Patients with hypertension and evidence of target organ damage such as liver, kidney and heart; 3. Patients with one of the following diseases: (1) Patients with severe endocrine diseases such as hyperthyroidism; (2) Patients with severe anemia; (3) Patients with mental illness; 4. Patients who took ACEI, ARB and statins regularly in recent 2 months.

Design outcomes

Primary

MeasureTime frame
Uric acid;

Countries

China

Contacts

Public ContactKai Senghuang

Deyang People's Hospital

874102818@qq.com+86 19982423949

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026